The 24-year-old picked up the coveted prize for her portrayal of teenage drug addict Rue in HBO’s Euphoria.
That was no mean feat given her heavyweight competition.
Zendaya saw off Killing Eve’s Jodie Comer and Sandra Oh, Ozark’s Laura Linney, The Crown’s Olivia Colman and The Morning Show’s Jennifer Aniston.
“I know this feels like a really weird time to be celebrating,” she said at the virtual ceremony, surrounded by her family.
“But I just want to say there is hope in the young people out there – I know that our TV show doesn’t always feel like a great example of that – but there is hope in our young people and I just want to say to all my peers out there doing the work in the streets, ‘I see you, I admire you, I thank you.'”